by Perfectus Biomed | 2016, Molecular, Publications, Tissue Models
Abstract
A detailed investigation of eukaryotic signaling pathways affected by bacterial products is key to our understanding of host-pathogen interactions. Cytokine expression appears to be an important initial host cell response to many bacterial products, including...
by Perfectus Biomed | 2016, Biofilm, Medical Devices, Publications
Abstract: The opportunistic pathogen Acinetobacter baumannii is able to persist in the environment and is often multidrug resistant (MDR), causing difficulties in the treatment of infections. Here, we show that the two-component system AdeRS, which regulates the production...
by Perfectus Biomed | 2015 and older, Infectious Disease, Publications, Tissue Models, Virology
Abstract
Background: The vaginal microbiota can impact the susceptibility of women to bacterial vaginosis (BV) and sexually transmitted infections (STIs). BV is characterized by depletion of Lactobacillus spp., an overgrowth of anaerobes (often dominated by...
by Perfectus Biomed | 2015 and older, Publications, Tissue Models
Abstract
Measures to prevent sexual mucosal transmission are critically needed, particularly to prevent transmission to young women at high risk in the microepidemics in South Africa that disproportionally contribute to the continued pandemic. To that end,...
by Perfectus Biomed | 2015 and older, Publications, Tissue Models, Wound Care
Abstract
Mupirocin decolonization of nasal Staphylococcus aureus prior to surgery decreases surgical-site infections; however, treatment requires 5 days, compliance is low, and resistance occurs. In 2010, 3M Company introduced povidone-iodine (PVP-I)-based skin and...
