by Perfectus Biomed | 2015 and older, Infectious Disease, Publications, Tissue Models, Virology
Abstract
Background: The vaginal microbiota can impact the susceptibility of women to bacterial vaginosis (BV) and sexually transmitted infections (STIs). BV is characterized by depletion of Lactobacillus spp., an overgrowth of anaerobes (often dominated by...
by Perfectus Biomed | 2015 and older, Infectious Disease, Publications, Virology
Abstract
Background: Staphylococcus aureus causes serious infections in both hospital and community settings. Attempts have been made to prevent human infection through vaccination against bacterial cell-surface antigens; thus far all have failed. Here we show...
by Perfectus Biomed | 2015 and older, Publications, Virology
Abstract
While there has been great progress in treating HIV-1 infection, preventing transmission has thus far proven an elusive goal. Indeed, recent trials of a candidate vaccine and microbicide have been disappointing, both for want of efficacy and concerns about...
by Perfectus Biomed | 2015 and older, Publications, Virology
Abstract
Glycerol monolaurate (GML) is a fatty acid monoester that inhibits growth and exotoxin production of vaginal pathogens and cytokine production by vaginal epithelial cells. Because of these activities, and because of the importance of cytokine-mediated immune...
