by Perfectus Biomed | 2015 and older, Infectious Disease, Publications
Abstract
VanX is an induced zinc metallo d-Ala-d-Ala dipeptidase involved in the viable remodeling of bacterial cell wall that is essential for the development of VREF. Here we report two cyclic thiohydroxamic acid-based peptide analogs that were designed, synthesized...
by Perfectus Biomed | 2015 and older, Infectious Disease, Publications, Virology
Abstract
Background: Staphylococcus aureus causes serious infections in both hospital and community settings. Attempts have been made to prevent human infection through vaccination against bacterial cell-surface antigens; thus far all have failed. Here we show...
by Perfectus Biomed | 2015 and older, Infectious Disease, Publications, Tissue Models
Abstract
Aims: To develop a semi-high-throughput ex vivo mucosal model for determining efficacy and toxicity of antiseptics.
Methods and results: Explants (5 mm) from freshly excised, porcine vaginal mucosa were infected with methicillin-sensitive Staphylococcus aureus (1...
by Perfectus Biomed | 2015 and older, Infectious Disease, Publications
Evaluation of the health care system has identified the need for more efficient and productive use of resources for providing quality patient outcomes. The use of critical pathways has been well described in the nursing literature. The primary goal is to combine...
