by jennieritchie | 2015 and older, Publications
Abstract
Many exotoxins of gram positive bacteria, such as superantigens (staphylococcal enterotoxins, toxic shock syndrome toxin-1 [TSST-1], and streptococcal pyrogenic exotoxins) and anthrax toxin are bioterrorism agents that cause diseases by immunostimulation...
by Perfectus Biomed | 2015 and older, Publications
Abstract
Despite knowledge of the effects of toxic shock syndrome (TSS) toxin 1 (TSST-1) on the adaptive immune system, little is known about stimulation of the innate immune system, particularly epithelial cells. This study investigated the interactions of...
by Perfectus Biomed | 2015 and older, Publications
Abstract
Background: Purpura fulminans is an acute illness commonly associated with meningococcemia or invasive streptococcal disease, and it is typically characterized by disseminated intravascular coagulation (DIC) and purpuric skin lesions. In this article, we report...
by Perfectus Biomed | 2015 and older, Publications
Toxic shock syndrome (TSS) is an acute-onset, multisystem illness characterized by fever (>102°F), hypotension (systolic pressure, <90 mm of Hg), sunburn-like rash, peeling of the skin, and a variable multiorgan component that often initially appears flu-like,...
by jennieritchie | 2015 and older, Publications
Abstract
Twelve laboratory mutants and 32 ciprofloxacin-resistant isolates of Bacteroides fragilis were examined for the mechanism(s) of fluoroquinolone resistance. Five mutants had mutations in gyrA. One mutant and two clinical isolates contained a mutation...
by Perfectus Biomed | 2015 and older, Publications
Abstract
Objectives: To identify whether mutations in gyrA and gyrB confer fluoroquinolone resistance in Bacteroides fragilis.
Methods: Eight fluoroquinolone-resistant (FQR) strains were complemented with plasmid-mediated B....
