by Perfectus Biomed | 2015 and older, Microbiology Research, Publications, Wound Care
Abstract
Horse wounds have a high risk of becoming infected due to their environment. Infected wounds harbour diverse populations of microorganisms, however in some cases these microorganisms can be difficult to identify and fail to respond to antibiotic treatment, resulting...
by Perfectus Biomed | 2015 and older, Biofilm, Publications
Abstract
Staphylococcus aureus causes many diseases in humans, ranging from mild skin infections to serious, life-threatening, superantigen-mediated Toxic Shock Syndrome (TSS). S. aureus may be asymptomatically carried in the anterior nares or vagina or on the skin, serving...
by Perfectus Biomed | 2015 and older, Microbiology Research, Publications
Staphylococcus aureus initiates infections and produces virulence factors, including superantigens (SAgs), at mucosal surfaces. The SAg, Toxic Shock Syndrome Toxin-1 (TSST-1) induces cytokine secretion from epithelial cells, antigen presenting cells (APCs) and T lymphocytes,...
by Perfectus Biomed | 2015 and older, Microbiology Research, Publications
Abstract
Pulsed-field gel electrophoresis (PFGE) clonal type USA200 is the most widely disseminated Staphylococcus aureus colonizer of the nose and is a major cause of toxic shock syndrome (TSS). Exoproteins derived from these organisms have been suggested to contribute...
by Perfectus Biomed | 2015 and older, Microbiology Research, Publications
Abstract
Staphylococcus aureus is a major human pathogen capable of causing various diseases, from skin infections to life-threatening pneumonia and toxic shock syndrome. S. aureus exoproteins, including superantigens, contribute significantly to the pathogenesis of...
by Perfectus Biomed | 2015 and older, Publications, Tissue Models
Abstract
Background: Chlorhexidine gluconate (CHG) and povidone iodine (PI) are rarely used concurrently despite a lack of evidence regarding functional incompatibility of these agents.
Methods: CHG and PI, alone and combined, were evaluated against Staphylococcus...